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Profile of the tprK gene in primary syphilis patients based on next-generation sequencing

BACKGROUND: The highly variable tprK gene of Treponema pallidum has been acknowledged to be one of the mechanisms that causes persistent infection. Previous studies have mainly focused on the heterogeneity in tprK in propagated strains using a clone-based Sanger approach. Few studies have investigat...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Liu, Dan, Tong, Man-Li, Luo, Xi, Liu, Li-Li, Lin, Li-Rong, Zhang, Hui-Lin, Lin, Yong, Niu, Jian-Jun, Yang, Tian-Ci
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400401/
https://ncbi.nlm.nih.gov/pubmed/30789907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006855
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