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Urea-mediated dissociation alleviate the false-positive Treponema pallidum-specific antibodies detected by ELISA

The serological detection of antibodies to Treponema pallidum is essential to the diagnosis of syphilis. However, for the presence of cross-reaction, the specific antibody tests [e.g., enzyme-linked immunosorbent assay (ELISA)] always have false-positive results. In this study, we derived and valida...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Qiang, Lei, Yan, Lu, Xiaolan, Wang, Guangrong, Du, Qin, Guo, Xiaolan, Xing, Yan, Zhang, Guoyuan, Wang, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400370/
https://ncbi.nlm.nih.gov/pubmed/30835745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212893
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