In vitro and in silico multidimensional modeling of oncolytic tumor virotherapy dynamics

Tumor therapy with replication competent viruses is an exciting approach to cancer eradication where viruses are engineered to specifically infect, replicate, spread and kill tumor cells. The outcome of tumor virotherapy is complex due to the variable interactions between the cancer cell and virus p...

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Опубликовано в: :PLoS Comput Biol
Главные авторы: Berg, David R., Offord, Chetan P., Kemler, Iris, Ennis, Matthew K., Chang, Lawrence, Paulik, George, Bajzer, Zeljko, Neuhauser, Claudia, Dingli, David
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400333/
https://ncbi.nlm.nih.gov/pubmed/30835721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006773
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