Pyridoxamine Treatment of HK-2 Human Proximal Tubular Epithelial Cells Reduces Oxidative Stress and the Inhibition of Autophagy Induced by High Glucose Levels

BACKGROUND: Diabetic nephropathy is a predominant cause of renal failure, which is an important chronic complication of diabetes. Pyridoxamine (PM) has been reported to protect renal tubular epithelial cells against oxidative damage and delay or inhibit the development and generation of glucose-indu...

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Vydáno v:Med Sci Monit
Hlavní autoři: Wang, Ying, Li, Ying, Yang, Zhiping, Wang, Ziqiang, Chang, Jiang, Zhang, Tao, Chi, Yanqing, Han, Ning, Zhao, Kunxiao
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
Lab/In Vitro Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400021/
https://ncbi.nlm.nih.gov/pubmed/30799433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.914799
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