Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy

BACKGROUND: The cytosine deaminase (CD)/5-fluorocytosine (5-FC) system is among the best explored enzyme/prodrug systems in the field of the suicide gene therapy. Recently, by the screening of the environmental metagenomic libraries we identified a novel isocytosine deaminase (ICD), termed Vcz, whic...

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Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Kazlauskas, Arunas, Darinskas, Adas, Meškys, Rolandas, Tamašauskas, Arimantas, Urbonavičius, Jaunius
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399854/
https://ncbi.nlm.nih.gov/pubmed/30832616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5409-7
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