Metformin Promotes Neuronal Differentiation via Crosstalk between Cdk5 and Sox6 in Neuroblastoma Cells

Metformin has recently emerged as a key player in promotion of neuroblastoma differentiation and neurite outgrowth. However, molecular mechanisms of how metformin promotes cellular differentiation have not yet been fully elucidated. In this study, we investigated how metformin promotes cell differen...

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Veröffentlicht in:Evid Based Complement Alternat Med
Hauptverfasser: Binlateh, Thunwa, Tanasawet, Supita, Rattanaporn, Onnicha, Sukketsiri, Wanida, Hutamekalin, Pilaiwanwadee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399528/
https://ncbi.nlm.nih.gov/pubmed/30911317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1765182
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