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Calcium-Phosphate Crystals Promote RANKL Expression via the Downregulation of DUSP1

Osteoarthritis (OA) is a naturally occurring, irreversible disorder and a major health burden. The disease is multifactorial, involving both physiological and mechanical processes, but calcium crystals have been associated intimately with its pathogenesis. This study tested the hypothesis that these...

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Опубликовано в: :Mol Cells
Главные авторы: Choi, YunJeong, Yoo, Ji Hyun, Lee, Youngkyun, Bae, Moon Kyoung, Kim, Hyung Joon
Формат: Artigo
Язык:Inglês
Опубликовано: Korean Society for Molecular and Cellular Biology 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399012/
https://ncbi.nlm.nih.gov/pubmed/30703868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2018.0382
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