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Rapid changes in morphogen concentration control self-organized patterning in human embryonic stem cells
During embryonic development, diffusible signaling molecules called morphogens are thought to determine cell fates in a concentration-dependent way. Yet, in mammalian embryos, concentrations change rapidly compared to the time for making cell fate decisions. Here, we use human embryonic stem cells (...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6398983/ https://ncbi.nlm.nih.gov/pubmed/30829572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40526 |
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