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Differential regulation of the unfolded protein response in outbred deer mice and susceptibility to metabolic disease

Endoplasmic reticulum (ER) stress has been causatively linked to the onset of various pathologies. However, whether and how inherent variations in the resulting unfolded protein response (UPR) affect predisposition to ER-stress-associated metabolic conditions remains to be established. By using gene...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Havighorst, Amanda, Zhang, Youwen, Farmaki, Elena, Kaza, Vimala, Chatzistamou, Ioulia, Kiaris, Hippokratis
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398494/
https://ncbi.nlm.nih.gov/pubmed/30733237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.037242
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