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Role of hepatocyte nuclear factor 4 alpha in cell proliferation and gemcitabine resistance in pancreatic adenocarcinoma

BACKGROUND: Hepatocyte nuclear factor 4α (HNF4α) is a tissue-specific transcription factor that regulates the expression of numerous genes in hepatocytes and pancreatic β cells. HNF4α has been reported to affect cell proliferation and chemoresistance in several cancers. However, the role of HNF4α in...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Cell Int
Päätekijät: Sun, Qiqing, Xu, Wenyan, Ji, Shunrong, Qin, Yi, Liu, Wensheng, Hu, Qiangsheng, Zhang, Zheng, Liu, Mengqi, Yu, Xianjun, Xu, Xiaowu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398265/
https://ncbi.nlm.nih.gov/pubmed/30867652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0767-4
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