HIV-Nef Protein Persists in the Lungs of Aviremic Patients with HIV and Induces Endothelial Cell Death

It remains a mystery why HIV-associated end-organ pathologies persist in the era of combined antiretroviral therapy (ART). One possible mechanism is the continued production of HIV-encoded proteins in latently HIV-infected T cells and macrophages. The proapoptotic protein HIV-Nef persists in the blo...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Chelvanambi, Sarvesh, Bogatcheva, Natalia V., Bednorz, Mariola, Agarwal, Stuti, Maier, Bernhard, Alves, Nathan J., Li, Wei, Syed, Farooq, Saber, Manal M., Dahl, Noelle, Lu, Hongyan, Day, Richard B., Smith, Patricia, Jolicoeur, Paul, Yu, Qigui, Dhillon, Navneet K., Weissmann, Norbert, Twigg III, Homer L., Clauss, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397978/
https://ncbi.nlm.nih.gov/pubmed/30321057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0089OC
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