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Modeling the structural and dynamical changes of the epithelial calcium channel TRPV5 caused by the A563T variation based on the structure of TRPV6
TRPV5 is an epithelial Ca(2+) channel that plays a key role in the active Ca(2+) reabsorption process in the kidney. A single nucleotide polymorphism (SNP) rs4252499 in the TRPV5 gene results in an A563T variation in the sixth transmembrane (TM) domain of TRPV5. Our previous study indicated that thi...
Gespeichert in:
Veröffentlicht in: | J Biomol Struct Dyn |
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Hauptverfasser: | , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2018
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6397782/ https://ncbi.nlm.nih.gov/pubmed/30175942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2018.1518790 |
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