DPP-4 inhibition enhanced renal tubular and myocardial GLP-1 receptor expression decreased in CKD with myocardial infarction

BACKGROUND: Chronic kidney disease (CKD) is strongly associated with cardiovascular disease and is a significant risk factor for increased morbidity and mortality. In contrast, GLP-1 receptor (GLP-1R) activation has been shown to confer both renal and cardiovascular protection, though its relationsh...

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Bibliografiske detaljer
Udgivet i:BMC Nephrol
Main Authors: Kim, Seung Jung, Kwon, Soon Kil, Kim, Hye-Young, Kim, Sun Moon, Bae, Jang-Whan, Choi, Joong-Kook
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397488/
https://ncbi.nlm.nih.gov/pubmed/30823876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-019-1243-z
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