Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle

Lifelong regular physical activity is associated with reduced risk of type 2 diabetes (T2D), maintenance of muscle mass and increased metabolic capacity. However, little is known about epigenetic mechanisms that might contribute to these beneficial effects in aged individuals. We investigated the ef...

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Publicado en:Sci Rep
Autores principales: Sailani, M. Reza, Halling, Jens Frey, Møller, Henrik Devitt, Lee, Hayan, Plomgaard, Peter, Pilegaard, Henriette, Snyder, Michael P., Regenberg, Birgitte
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397284/
https://ncbi.nlm.nih.gov/pubmed/30824849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37895-8
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