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Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle

Lifelong regular physical activity is associated with reduced risk of type 2 diabetes (T2D), maintenance of muscle mass and increased metabolic capacity. However, little is known about epigenetic mechanisms that might contribute to these beneficial effects in aged individuals. We investigated the ef...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Sailani, M. Reza, Halling, Jens Frey, Møller, Henrik Devitt, Lee, Hayan, Plomgaard, Peter, Pilegaard, Henriette, Snyder, Michael P., Regenberg, Birgitte
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397284/
https://ncbi.nlm.nih.gov/pubmed/30824849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37895-8
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