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Long term safety of targeted internalization of cell penetrating peptide crotamine into renal proximal tubular epithelial cells in vivo

Activated proximal tubular epithelial cells (PTECs) play a crucial role in progressive tubulo-interstitial fibrosis in native and transplanted kidneys. Targeting PTECs by non-viral delivery vectors might be useful to influence the expression of important genes and/or proteins in order to slow down r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Campeiro, Joana Darc, Dam, Wendy, Monte, Gabriela Guilherme, Porta, Lucas Carvalho, Oliveira, Lilian Caroline Gonçalves de, Nering, Marcela Bego, Viana, Gustavo Monteiro, Carapeto, Fernando Cintra, Oliveira, Eduardo Brandt, van den Born, Jacob, Hayashi, Mirian A. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397221/
https://ncbi.nlm.nih.gov/pubmed/30824773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39842-7
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