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Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7
P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens such as Mycobacterium tuberculosis and Toxoplasma gondii. Enhancement of P2X7 receptor responses may be useful in pathogen clearance particularly in individuals with defective mic...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6397193/ https://ncbi.nlm.nih.gov/pubmed/30824738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39771-5 |
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