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Myocardial lipofuscin accumulation in ageing and sudden cardiac death

Lipofuscin is an intracellular aggregate of highly oxidized proteins that cannot be digested in the ubiquitin-proteasome system and accumulate mainly in lysosomes, especially in aged cells and pathological conditions. However, no systematic study has evaluated the cardiac accumulation of lipofuscin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Kakimoto, Yu, Okada, Chisa, Kawabe, Noboru, Sasaki, Ayumi, Tsukamoto, Hideo, Nagao, Ryoko, Osawa, Motoki
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397159/
https://ncbi.nlm.nih.gov/pubmed/30824797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40250-0
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