TRPM7 promotes the epithelial–mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling

BACKGROUND: The epithelial-mesenchymal transition (EMT) is crucial for metastasis and positively regulated by calcium-related signaling. The melastatin-related transient receptor potential 7 (TRPM7) regulates a non-selective cation channel and promotes cancer metastasis. However, the mechanisms unde...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Liu, Lu, Wu, Nayiyuan, Wang, Ying, Zhang, Xiaoyun, Xia, Bing, Tang, Jie, Cai, Jingting, Zhao, Zitong, Liao, Qianjin, Wang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396458/
https://ncbi.nlm.nih.gov/pubmed/30819230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1061-y
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