A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis

Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies. This phase 2 study assessed the efficacy and safety of maralixibat, a selective, ileal, apical, sodium‐dependent, bile a...

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Pubblicato in:Hepatol Commun
Autori principali: Mayo, Marlyn J., Pockros, Paul J., Jones, David, Bowlus, Christopher L., Levy, Cynthia, Patanwala, Imran, Bacon, Bruce, Luketic, Velimir, Vuppalanchi, Raj, Medendorp, Sharon, Dorenbaum, Alejandro, Kennedy, Ciara, Novak, Patricia, Gu, Joan, Apostol, George, Hirschfield, Gideon M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396374/
https://ncbi.nlm.nih.gov/pubmed/30859149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1305
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