Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease

Alcoholic fatty liver disease (AFLD) is a growing health problem for which no targeted therapy is available. We set out to study whether systemic inactivation of the main hypoxia-inducible factor prolyl 4-hydroxylase, HIF-P4H-2 (PHD2/EglN1), whose inactivation has been associated with protection aga...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Laitakari, Anna, Ollonen, Teemu, Kietzmann, Thomas, Walkinshaw, Gail, Mennerich, Daniela, Izzi, Valerio, Haapasaari, Kirsi-Maria, Myllyharju, Johanna, Serpi, Raisa, Dimova, Elitsa Y., Koivunen, Peppi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396018/
https://ncbi.nlm.nih.gov/pubmed/30802717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101145
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