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Dying neurons utilize innate immune signaling to prime glia for phagocytosis during development

Glia continuously survey neuronal health during development, providing trophic support to healthy neurons while rapidly engulfing dying ones. These diametrically-opposed functions necessitate a foolproof mechanism enabling glia to unambiguously identify those neurons to support versus those to engul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dev Cell
Prif Awduron: McLaughlin, Colleen N., Perry-Richardson, Jahci J., Coutinho-Budd, Jaeda C., Broihier, Heather T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6394877/
https://ncbi.nlm.nih.gov/pubmed/30745142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.12.019
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