Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation

Mycobacterium bovis, the causative agent of tuberculosis in cattle and humans, infects host macrophages and induces endoplasmic reticulum stress (ERS), mitochondrial damage, and interleukin (IL)-1β production. The relationship between these phenotypes is yet to be elucidated. In this study, we inves...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Liao, Yi, Hussain, Tariq, Liu, Chunfa, Cui, Yongyong, Wang, Jie, Yao, Jiao, Chen, Hehua, Song, Yinjuan, Sabir, Naveed, Hussain, Mazhar, Zhao, Deming, Zhou, Xiangmei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6394253/
https://ncbi.nlm.nih.gov/pubmed/30846986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00268
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