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An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder

Nicotinic acetylcholine receptors (nAChRs), particularly the α7 nAChR, are implicated in the pathophysiology of both autism spectrum disorder (ASD) and aggressive behavior. We explored the feasibility, tolerability, and preliminary efficacy of targeting nAChRs using transdermal nicotine to reduce ag...

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Bibliographische Detailangaben
Veröffentlicht in:J Autism Dev Disord
Hauptverfasser: Lewis, Alan S., van Schalkwyk, Gerrit Ian, Lopez, Mayra Ortiz, Volkmar, Fred R., Picciotto, Marina R., Sukhodolsky, Denis G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6394231/
https://ncbi.nlm.nih.gov/pubmed/29536216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10803-018-3536-7
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