Deprivation of the Periplasmic Chaperone SurA Reduces Virulence and Restores Antibiotic Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa

Pseudomonas aeruginosa is one of the main causative agents of nosocomial infections and the spread of multidrug-resistant strains is rising. Therefore, novel strategies for therapy are urgently required. The outer membrane composition of Gram-negative pathogens and especially of Pa restricts the eff...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Klein, Kristina, Sonnabend, Michael S., Frank, Lisa, Leibiger, Karolin, Franz-Wachtel, Mirita, Macek, Boris, Trunk, Thomas, Leo, Jack C., Autenrieth, Ingo B., Schütz, Monika, Bohn, Erwin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6394205/
https://ncbi.nlm.nih.gov/pubmed/30846971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00100
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