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Preclinical Safety Evaluation of Ophthalmic Viscosurgical Devices in Rabbits and a Novel Mini-Pig Model

INTRODUCTION: To establish the preclinical safety and equivalency of ophthalmic viscosurgical devices (OVDs) comprised of bacterially sourced sodium hyaluronate (HA) to animal sourced HA using pyrogenicity and aqueous exchange models in rabbits and a novel mini-pig model to evaluate corneal endothel...

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Detalhes bibliográficos
Publicado no:Ophthalmol Ther
Main Authors: Leang, Ronika S., Kloft, Lisa J., Gray, Brad, Gwon, Arlene E., Huang, Ling C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6393256/
https://ncbi.nlm.nih.gov/pubmed/30778776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40123-019-0167-9
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