G6Pase location in the endoplasmic reticulum: Implications on compartmental analysis of FDG uptake in cancer cells

The favourable kinetics of (18)F-fluoro-2-deoxyglucose (FDG) permits to depict cancer glucose consumption by a single evaluation of late tracer uptake. This standard procedure relies on the slow radioactivity loss, usually attributed to the limited tumour expression of G6P-phosphatase (G6Pase). Howe...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Scussolini, Mara, Bauckneht, Matteo, Cossu, Vanessa, Bruno, Silvia, Orengo, Anna Maria, Piccioli, Patrizia, Capitanio, Selene, Yosifov, Nikola, Ravera, Silvia, Morbelli, Silvia, Piana, Michele, Sambuceti, Gianmario, Caviglia, Giacomo, Marini, Cecilia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6391477/
https://ncbi.nlm.nih.gov/pubmed/30808900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38973-1
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