Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: A prospective study with multilayer non-negative matrix factorization

BACKGROUND: Joint inflammation is the common feature underlying juvenile idiopathic arthritis (JIA). Clinicians recognize patterns of joint involvement currently not part of the International League of Associations for Rheumatology (ILAR) classification. Using unsupervised machine learning, we sough...

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Veröffentlicht in:PLoS Med
Hauptverfasser: Eng, Simon W. M., Aeschlimann, Florence A., van Veenendaal, Mira, Berard, Roberta A., Rosenberg, Alan M., Morris, Quaid, Yeung, Rae S. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6390994/
https://ncbi.nlm.nih.gov/pubmed/30807586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002750
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