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Empagliflozin Improves Diastolic Function in a Nondiabetic Rodent Model of Heart Failure With Preserved Ejection Fraction

Recent studies send an unambiguous signal that the class of agents known as sodium-glucose–linked co-transporter-2 inhibitors (SGLT2i) prevent heart failure hospitalization in patients with type 2 diabetes. However, the mechanisms remain unclear. Herein the authors utilize a rodent model of heart fa...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Connelly, Kim A., Zhang, Yanling, Visram, Aylin, Advani, Andrew, Batchu, Sri N., Desjardins, Jean-François, Thai, Kerri, Gilbert, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6390677/
https://ncbi.nlm.nih.gov/pubmed/30847416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.11.010
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