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Sodium azide induces mitochondria-mediated apoptosis in PC12 cells through Pgc-1α-associated signaling pathway
Sodium azide (NaN(3)), an inhibitor of cytochrome oxidase, induces the release of excitotoxins via an energy impairment and this, in turn, results in neurodegeneration. The present study aimed to investigate the toxic effects NaN(3) on apoptosis of PC12 cells and its mechanism of action in peroxisom...
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| 發表在: | Mol Med Rep |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
D.A. Spandidos
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6390015/ https://ncbi.nlm.nih.gov/pubmed/30664159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.9853 |
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