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By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans

Global production of pharmaceutical heparin (Hp) is increasing, and the production process from raw mucosal material results in large amounts of waste by-products. These contain lower sulfated Hp-like and heparan sulfate (HS), as well as other glycosaminoglycans, which are bioactive entities with ph...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Taylor, Sarah L., Hogwood, John, Guo, Wei, Yates, Edwin A., Turnbull, Jeremy E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389988/
https://ncbi.nlm.nih.gov/pubmed/30804383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39093-6
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