Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice

Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal bonding behaviours. Mice lacking secreted oxcytocin (Oxt(−/−), Cd38(−/−)) or its receptor (Oxtr(−/−)) fail to nurture. Normal maternal behaviour is restored by peripheral oxcytocin replacement in Oxt(−/...

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Publicado no:Commun Biol
Main Authors: Yamamoto, Yasuhiko, Liang, Mingkun, Munesue, Seiichi, Deguchi, Kisaburo, Harashima, Ai, Furuhara, Kazumi, Yuhi, Teruko, Zhong, Jing, Akther, Shirin, Goto, Hisanori, Eguchi, Yuya, Kitao, Yasuko, Hori, Osamu, Shiraishi, Yoshitake, Ozaki, Noriyuki, Shimizu, Yu, Kamide, Tomoya, Yoshikawa, Akifumi, Hayashi, Yasuhiko, Nakada, Mitsutoshi, Lopatina, Olga, Gerasimenko, Maria, Komleva, Yulia, Malinovskaya, Natalia, Salmina, Alla B., Asano, Masahide, Nishimori, Katsuhiko, Shoelson, Steven E., Yamamoto, Hiroshi, Higashida, Haruhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389896/
https://ncbi.nlm.nih.gov/pubmed/30820471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0325-6
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