Glomerular membrane attack complex is not a reliable marker of ongoing C5 activation in lupus nephritis

Complement plays an important role in the pathogenesis of lupus nephritis (LN). With the emergence of therapeutic complement inhibition, there is a need to identify patients in whom complement-driven inflammation is a major cause of kidney injury in LN. Clinical and histopathological data were obtai...

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Publicat a:Kidney Int
Autors principals: Wilson, Hannah R., Medjeral-Thomas, Nicholas R., Gilmore, Alyssa C., Trivedi, Pritesh, Seyb, Kathleen, Farzaneh-Far, Ramin, Gunnarsson, Iva, Zickert, Agneta, Cairns, Thomas D., Lightstone, Liz, Cook, H. Terence, Pickering, Matthew C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389546/
https://ncbi.nlm.nih.gov/pubmed/30655025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2018.09.027
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