HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses

BACKGROUND: Denervation triggers numerous molecular responses in skeletal muscle, including the activation of catabolic pathways and oxidative stress, leading to progressive muscle atrophy. Histone deacetylase 4 (HDAC4) mediates skeletal muscle response to denervation, suggesting the use of HDAC inh...

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Podrobná bibliografie
Vydáno v:Skelet Muscle
Hlavní autoři: Pigna, Eva, Renzini, Alessandra, Greco, Emanuela, Simonazzi, Elena, Fulle, Stefania, Mancinelli, Rosa, Moresi, Viviana, Adamo, Sergio
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389241/
https://ncbi.nlm.nih.gov/pubmed/29477142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-018-0153-2
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