HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses

BACKGROUND: Denervation triggers numerous molecular responses in skeletal muscle, including the activation of catabolic pathways and oxidative stress, leading to progressive muscle atrophy. Histone deacetylase 4 (HDAC4) mediates skeletal muscle response to denervation, suggesting the use of HDAC inh...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Skelet Muscle
Main Authors: Pigna, Eva, Renzini, Alessandra, Greco, Emanuela, Simonazzi, Elena, Fulle, Stefania, Mancinelli, Rosa, Moresi, Viviana, Adamo, Sergio
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389241/
https://ncbi.nlm.nih.gov/pubmed/29477142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-018-0153-2
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