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Better ILP models for haplotype assembly

BACKGROUND: The haplotype assembly problem for diploid is to find a pair of haplotypes from a given set of aligned Single Nucleotide Polymorphism (SNP) fragments (reads). It has many applications in association studies, drug design, and genetic research. Since this problem is computationally hard, b...

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Pubblicato in:BMC Bioinformatics
Autori principali: Etemadi, Maryam, Bagherian, Mehri, Chen, Zhi-Zhong, Wang, Lusheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389102/
https://ncbi.nlm.nih.gov/pubmed/29504891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2012-x
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