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Protocadherin 17 is a tumor suppressor and is frequently methylated in nasopharyngeal carcinoma

PURPOSE: Several PCDH genes were shown to be downregulated or silenced in carcinomas and act as candidate tumor suppressor genes. However, the functions of PCDH17 in nasopharyngeal carcinoma (NPC) remain unclear. Here, we investigated the PCDH17 promoter methylation status and its impact on the expr...

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Dettagli Bibliografici
Pubblicato in:Cancer Manag Res
Autori principali: He, Ya, Wang, Zhihai, Liu, Chuan, Gong, Zhitao, Li, Yanshi, Lu, Tao, Hu, Guohua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388982/
https://ncbi.nlm.nih.gov/pubmed/30863170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S191102
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