Characterization of an Inducible Alcoholic Liver Fibrosis Model for Hepatocellular Carcinoma Investigation in a Transgenic Porcine Tumorigenic Platform

PURPOSE: This study used the Oncopig Cancer Model (OCM) to develop alcohol-induced fibrosis in a porcine model capable of developing hepatocellular carcinoma. MATERIALS AND METHODS: Liver injury was induced in 8-week-old Oncopigs (n = 10) via hepatic transarterial infusion of 0.75 mL/kg ethanol-ethi...

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Publicado en:J Vasc Interv Radiol
Main Authors: Gaba, Ron C., Mendoza-Elias, Nasya, Regan, Daniel P., Garcia, Kelly D., Lokken, R. Peter, Schwind, Regina M., Eichner, Michael, Thomas, Faith M., Rund, Lauretta A., Schook, Lawrence B., Schachtschneider, Kyle M.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388685/
https://ncbi.nlm.nih.gov/pubmed/29887183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvir.2018.03.007
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