Intra-articular Injection of a Substance P Inhibitor Affects Gene Expression in a Joint Contracture Model

Substance P (SP), a neurotransmitter released after injury, has been linked to deregulated tissue repair and fibrosis in musculoskeletal tissues and other organs. Although SP inhibition is an effective treatment for nausea, it has not been previously considered as an anti-fibrotic therapy. Although...

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Опубликовано в: :J Cell Biochem
Главные авторы: Morrey, Mark E., Sanchez-Sotelo, Joaquin, Lewallen, Eric A., An, Kai-Nan, Grill, Diane E., Steinmann, Scott P., Yao, Jie J., Salib, Christopher G., Trousdale, William H., Reina, Nicolas, Kremers, Hilal M., Lewallen, David G., van Wijnen, Andre J., Abdel, Matthew P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388635/
https://ncbi.nlm.nih.gov/pubmed/28671282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26256
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