Usnea Acid as Multidrug Resistance (MDR) Reversing Agent against Human Chronic Myelogenous Leukemia K562/ADR Cells via an ROS Dependent Apoptosis

PURPOSE: Multidrug resistance (MDR) is a major obstacle in chemotherapy of leukemia treatments. In this paper, we investigated Usnea Acid (UA) as MDR reversal agent on hematologic K562/ADR cells via ROS dependent apoptosis. METHODS: CCK8 assay was used to measure cell viability rate of K562/ADR. Int...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Wang, Wenjing, Niu, Shubin, Qiao, Luxin, Wei, Feili, Yin, Jiming, Wang, Shanshan, Ouyang, Yabo, Chen, Dexi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388510/
https://ncbi.nlm.nih.gov/pubmed/30886864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8727935
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