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Identification of the Germline Mutation Profile in Esophageal Squamous Cell Carcinoma by Whole Exome Sequencing

Background: Esophageal squamous cell carcinoma (ESCC) is associated with poor prognosis and occurs with high frequency in China. The germline mutation profile in ESCC remains unclear, and therefore, the discovery of oncogenic alterations in ESCC is urgently needed. This study investigates the germli...

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Опубликовано в: :Front Genet
Главные авторы: Deng, Jiaying, Weng, Xiaoling, Ye, Junyi, Zhou, Daizhan, Liu, Yun, Zhao, Kuaile
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387948/
https://ncbi.nlm.nih.gov/pubmed/30833958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00047
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