In vitro Liver Zonation of Primary Rat Hepatocytes

The ability of the liver to simultaneously carry out multiple functions is dependent on the metabolic heterogeneity of hepatocytes spatially located within a liver lobule spanning from the portal triad to the central vein. This complex zonal architecture of the liver, however, makes accurate in vitr...

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Tomlinson, Lauren, Hyndman, Lauren, Firman, James W., Bentley, Robert, Kyffin, Jonathan A., Webb, Steven D., McGinty, Sean, Sharma, Parveen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387900/
https://ncbi.nlm.nih.gov/pubmed/30834246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00017
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