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Behavioral analysis of SNAP-25 and Synaptobrevin-2 haploinsufficiency in mice

In central synapses, synaptobrevin-2 (also called VAMP-2) is the predominant synaptic vesicle SNARE protein that interacts with the plasma membrane SNAREs, SNAP-25 and syntaxin-1 to execute exocytosis. Mice deficient in synaptobrevin-2 or SNAP-25 show embryonic lethality, which precludes investigati...

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Bibliografiske detaljer
Udgivet i:Neuroscience
Main Authors: Monteggia, Lisa M., Lin, Pei-Yi, Adachi, Megumi, Kavalali, Ege T.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387657/
https://ncbi.nlm.nih.gov/pubmed/30144509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.08.014
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