Prognostic and predictive value of androgen receptor expression in postmenopausal women with estrogen receptor-positive breast cancer: results from the Breast International Group Trial 1–98

BACKGROUND: The androgen receptor (AR) is an emerging prognostic marker and therapeutic target in breast cancer. AR is expressed in 60–80% of breast cancers, with higher prevalence among estrogen receptor-positive (ER+) tumors. Androgen treatment inhibits ER signaling in ER+/AR+ breast cancer cell l...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Kensler, Kevin H., Regan, Meredith M., Heng, Yujing J., Baker, Gabrielle M., Pyle, Michael E., Schnitt, Stuart J., Hazra, Aditi, Kammler, Roswitha, Thürlimann, Beat, Colleoni, Marco, Viale, Giuseppe, Brown, Myles, Tamimi, Rulla M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387478/
https://ncbi.nlm.nih.gov/pubmed/30795773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1118-z
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