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Localized Delivery of Pilocarpine to Hypofunctional Salivary Glands through Electrospun Nanofiber Mats: An Ex Vivo and In Vivo Study

Dry mouth or xerostomia is a frequent medical condition among the polymedicated elderly population. Systemic pilocarpine is included in the first line of pharmacological therapies for xerostomia. However, the efficacy of existing pilocarpine formulations is limited due to its adverse side effects an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Muthumariappan, Sujatha, Ng, Wei Cheng, Adine, Christabella, Ng, Kiaw Kiaw, Davoodi, Pooya, Wang, Chi-Hwa, Ferreira, Joao N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387464/
https://ncbi.nlm.nih.gov/pubmed/30696017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030541
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