Clonal Hematopoiesis with Oncogenic Potential (CHOP): Separation from CHIP and Roads to AML

The development of leukemia is a step-wise process that is associated with molecular diversification and clonal selection of neoplastic stem cells. Depending on the number and combinations of lesions, one or more sub-clones expand/s after a variable latency period. Initial stages may develop early i...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Valent, Peter, Kern, Wolfgang, Hoermann, Gregor, Milosevic Feenstra, Jelena D., Sotlar, Karl, Pfeilstöcker, Michael, Germing, Ulrich, Sperr, Wolfgang R., Reiter, Andreas, Wolf, Dominik, Arock, Michel, Haferlach, Torsten, Horny, Hans-Peter
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387423/
https://ncbi.nlm.nih.gov/pubmed/30759825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030789
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