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Quantifying BRCA1 and BRCA2 mRNA Isoform Expression Levels in Single Cells

BRCA1 and BRCA2 spliceogenic variants are often associated with an elevated risk of breast and ovarian cancers. Analyses of BRCA1 and BRCA2 splicing patterns have traditionally used technologies that sample a population of cells but do not account for the variation that may be present between indivi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lattimore, Vanessa L., Pearson, John F., Morley-Bunker, Arthur E., Investigators, kConFab, Spurdle, Amanda B., Robinson, Bridget A., Currie, Margaret J., Walker, Logan C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387195/
https://ncbi.nlm.nih.gov/pubmed/30736279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030693
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