Inhibition of Heme Oxygenase-1 Activity Enhances Wilms Tumor-1-Specific T-Cell Responses in Cancer Immunotherapy

Wilms tumor protein-1 (WT1) is an attractive target for adoptive T-cell therapy due to its expression in solid tumors and hematologic malignancies. However, T cells recognizing WT1 occur in low frequencies in the peripheral blood of healthy donors, limiting potential therapeutic possibilities. Tin m...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Schillingmann, Damaris A., Riese, Sebastian B., Vijayan, Vijith, Tischer-Zimmermann, Sabine, Schmetzer, Helga, Maecker-Kolhoff, Britta, Blasczyk, Rainer, Immenschuh, Stephan, Eiz-Vesper, Britta
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387130/
https://ncbi.nlm.nih.gov/pubmed/30678050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030482
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