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TRAF6 Silencing Attenuates Multiple Myeloma Cell Adhesion to Bone Marrow Stromal Cells

The bone marrow (BM) microenvironment plays an important role in supporting proliferation, survival and drug resistance of Multiple Myeloma (MM) cells. MM cells adhere to bone marrow stromal cells leading to the activation of tumour-promoting signaling pathways. Activation of the NFκB pathway, in pa...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Morgan, Jonathan J., McAvera, Roisin M., Crawford, Lisa J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387103/
https://ncbi.nlm.nih.gov/pubmed/30736330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030702
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