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Bisoprolol, Known to Be a Selective β(1)-Receptor Antagonist, Differentially but Directly Suppresses I(K(M)) and I(K(erg)) in Pituitary Cells and Hippocampal Neurons

Bisoprolol (BIS) is a selective antagonist of β(1) adrenergic receptors. We examined the effects of BIS on M-type K(+) currents (I(K(M))) or erg-mediated K(+) currents (I(K(erg))) in pituitary GH(3,) R1220 cells, and hippocampal mHippoE-14 cells. As GH(3) cells were exposed to BIS, amplitude of I(K(...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: So, Edmund Cheung, Foo, Ning-Ping, Ko, Shun Yao, Wu, Sheng-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386942/
https://ncbi.nlm.nih.gov/pubmed/30717422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030657
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