Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain laterality/asymmetry in schizophrenia and bipolar disorder

INTRODUCTION: Although the loss or reversal of brain laterality is one of the most consistent modalities in schizophrenia (SCZ) and bipolar disorder (BD), its molecular basis remains elusive. Our limited previous studies indicated that epigenetic modifications are key to the asymmetric transcriptome...

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Библиографические подробности
Опубликовано в: :Am J Med Genet B Neuropsychiatr Genet
Главные авторы: Abdolmaleky, Hamid Mostafavi, Gower, Adam Chapin, Wong, Chen Khuan, Cox, Jiayi Wu, Zhang, Xiaoling, Thiagalingam, Arunthathi, Shafa, Rahim, Sivaraman, Vadivelu, Zhou, Jin-Rong, Thiagalingam, Sam
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386618/
https://ncbi.nlm.nih.gov/pubmed/30468562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32691
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