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Targeting mTOR and Src restricts hepatocellular carcinoma growth in a novel murine liver cancer model
Liver cancer is a poor prognosis cancer with limited treatment options. To develop a new therapeutic approach, we derived HCC cells from a known model of murine hepatocellular carcinoma (HCC). We treated adiponectin (APN) knock-out mice with the carcinogen diethylnitrosamine, and the resulting tumor...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6386388/ https://ncbi.nlm.nih.gov/pubmed/30794695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212860 |
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